Biochemistry Department

Martinez Research Group

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Welcome to the Martinez Research Group

Our general research interest is in the characterization of the basic molecular mechanisms of mammalian gene regulation at the transcriptional level with a focus on the chromatin/epigenetic signaling and transcription regulatory processes that control cell growth and differentiation and that contribute to cancer formation. Our research focuses on 3 interrelated projects: (i) Study of the cell and molecular functions of GCN5/PCAF histone acetyltransferase complexes; (ii) Identification and characterization of coregulators that control the transcription and cell biological functions of the MYC oncoprotein in normal and cancer cells; and (iii) Identification and characterization of the factors and molecular mechanisms involved in core promoter function and core promoter-dependent regulation of specific gene transcription by RNA polymerase II. A combination of cellular and molecular approaches are used.

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General Campus Information

University of California, Riverside
900 University Ave.
Riverside, CA 92521
Tel: (951) 827-1012

Career OpportunitiesUCR Libraries
Campus StatusDirections to UCR

Department Information

Department of Biochemistry
1463 Boyce Hall

Department Chair's Tel: (951) 827-3598
Fax: (951) 827-2364
Email: Biochem@ucr.edu

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